Tu uvadzam clanok, kde pisu, ze sa maju pouzivat probiotika s antibiotikami(najlepsie na noc aspon 3 hodiny po pouziti atb alebo silnych antimikrobialnych vo vacsich davkach). Vysledky vyskumu jasne naznacuju, ze je to spravne.


Probiotics Help Offset Side Effects of Antibiotics

By Greg Arnold, DC, CSCS, December 29, 2008, abstracted from “Probiotics” in the December 2008 issue of American Family Physician

Probiotics are defined as “good” bacteria that can help maintain health when given in adequate amounts (1). The most widely used and thoroughly researched organisms are the class of bacteria called Lactobacillus (L. acidophilus, L. rhamnosus, L. bulgaricus, L. reuteri, L. casei), and Bifidobacterium. Current recommendations regarding dosage are 5 to 10 billion colony-forming units (CFUs) per day for children and 10-20 billion CFUs per day for adults.

Probiotics have been shown to produce a number of health benefits, including helping deal with traveling sickness (2, maintaining digestive health during chronic stress (3), helping allergy health in newborns (4), helping patients with crohn’s disease (5), as well as lung health, (6) and bone health (7). Probiotics have even been found to benefit the elderly (8). Now a new study (9) has found that probiotics may help offset some side effects of taking antibiotics.

In the study, researchers analyzed data from two “meta-analysis” studies concerning the effects of probiotics on antibiotic-induced diarrhea (10, 11). In the first meta-analysis, which covered 19 different studies (10), probiotics reduced antibiotic-induced diarrhea by 52% . The greatest benefit was seen when the probiotics were started within 3 days of the onset of antibiotic treatment and included strains of L. rhamnosus and L. acidophilus.

In the second meta-analysis, which reviewed 25 studies and covered over 2,800 patients (11), probiotics reduced the risk of developing antibiotic-induced diarrhea by 57% with doses of 3 billion CFUs per day. However, studies using more than 10 billion CFUs per day showed that these dosages were significantly more effective.

Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at or visiting his web site at

1. Food and Agriculture Organization of the United Nations and the World Health Organization. Health and nutritional properties of probiotics in food including powder milk with live lactic acid bacteria. Cordoba, Argentina; 2001.
2. Paton, A. W., M. P. Jennings, et al. (2005). "Recombinant Probiotics for Treatment and Prevention of Enterotoxigenic Escherichia coli Diarrhea." Gastroenterology 128(5): 1219-28
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5. Shunji Fujimori. High dose probiotic and prebiotic cotherapy for remission induction of active Crohn’s disease. Jou Gastroenterol Hepatol 2007; 22(8): 1199–1204
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7. Abrams, S. A., I. J. Griffin, et al. (2005). "A combination of prebiotic short- and long-chain inulin-type fructans enhances calcium absorption and bone mineralization in young adolescents." Am J Clin Nutr 82(2): 471-6
8. Hamilton-Miller JMT Probiotics and prebiotics in the elderly Postgrad. Med. J., Aug 2004; 80: 447 – 451d
9. Kligler B. Probiotics. Am Fam Physician. 2008;78(9):1073-1078
10. Sazawal S, Hiremath G, Dhingra U, Malik P, Deb S, Black RE. Efficacy of probiotics in prevention of acute diarrhoea: a meta-analysis of masked, randomised, placebocontrolled trials. Lancet Infect Dis. 2006;6(6):374-382
11. McFarland LV. Meta-analysis of probiotics for the prevention of antibiotic associated diarrhea and the treatment of Clostridium difficile disease. Am J Gastroenterol. 2006;101(4):812-822.

10.04.2010 15:54:39
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